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RNA Virus Fidelity Mutants: A Useful Tool for Evolutionary Biology or a Complex Challenge?
RNA viruses replicate with low fidelity due to the error-prone nature of the RNA-dependent RNA polymerase, which generates approximately one mutation per round of genome replication. Due to the large population sizes produced by RNA viruses during replication, this results in a cloud of closely rela...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267201/ https://www.ncbi.nlm.nih.gov/pubmed/30388745 http://dx.doi.org/10.3390/v10110600 |