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Alzheimer’s Disease Phenotype or Inflammatory Insult Does Not Alter Function of L-Type Amino Acid Transporter 1 in Mouse Blood-Brain Barrier and Primary Astrocytes

PURPOSE: The study aim was to evaluate the effect of Alzheimer’s disease (AD) and inflammatory insult on the function of L-type amino acid transporter 1 (Lat1) at the mouse blood-brain barrier (BBB) as well as Lat1 function and expression in mouse primary astrocytes. METHODS: The Lat1 function and e...

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Detalles Bibliográficos
Autores principales: Gynther, Mikko, Puris, Elena, Peltokangas, Soile, Auriola, Seppo, Kanninen, Katja M., Koistinaho, Jari, Huttunen, Kristiina M., Ruponen, Marika, Vellonen, Kati-Sisko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267245/
https://www.ncbi.nlm.nih.gov/pubmed/30488131
http://dx.doi.org/10.1007/s11095-018-2546-7