Phylogenetic analysis and expression profiling of the Klotho gene family in the short-lived African killifish Nothobranchius furzeri

Members of the Klotho gene family have been identified as modulators of the aging process. Deletion of αklotho in the mouse results in a syndrome resembling rapid human aging. Conversely, overexpression of αklotho extends mammalian lifespan. Here, we identify klotho orthologs in the vertebrate aging...

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Detalles Bibliográficos
Autores principales: Zupkovitz, Gordin, Kabiljo, Julijan, Martin, David, Laffer, Sylvia, Schöfer, Christian, Pusch, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267267/
https://www.ncbi.nlm.nih.gov/pubmed/30178389
http://dx.doi.org/10.1007/s00427-018-0619-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267267/
https://www.ncbi.nlm.nih.gov/pubmed/30178389
http://dx.doi.org/10.1007/s00427-018-0619-6

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