Downregulation of TRAIL-Receptor 1 Increases TGFβ Type II Receptor Expression and TGFβ Signalling Via MicroRNA-370-3p in Pancreatic Cancer Cells

The accumulation of perturbations in signalling pathways resulting in an apoptosis-insensitive phenotype is largely responsible for the desperate prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). Accumulating evidence suggests that the death receptors TRAIL-R1 and TRAIL-R2 play imp...

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Detalles Bibliográficos
Autores principales: Radke, David I., Ling, Qi, Häsler, Robert, Alp, Gökhan, Ungefroren, Hendrik, Trauzold, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267290/
https://www.ncbi.nlm.nih.gov/pubmed/30366420
http://dx.doi.org/10.3390/cancers10110399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267290/
https://www.ncbi.nlm.nih.gov/pubmed/30366420
http://dx.doi.org/10.3390/cancers10110399

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