Generation of an anti-desmoglein 3 antibody without pathogenic activity of pemphigus vulgaris for therapeutic application to squamous cell carcinoma

It is ideal for the target antigen of a cytotoxic therapeutic antibody against cancer to be cancer-specific, but such antigens are rare. Thus an alternative strategy for target selection is necessary. Desmoglein 3 (DSG3) is highly expressed in lung squamous cell carcinoma, while it is well-known tha...

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Detalles Bibliográficos
Autores principales: Funahashi, Shin-Ichi, Kawai, Shigeto, Fujii, Etsuko, Taniguchi, Kenji, Nakano, Kiyotaka, Ishikawa, Shumpei, Aburatani, Hiroyuki, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Regular Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267343/
https://www.ncbi.nlm.nih.gov/pubmed/30239818
http://dx.doi.org/10.1093/jb/mvy074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267343/
https://www.ncbi.nlm.nih.gov/pubmed/30239818
http://dx.doi.org/10.1093/jb/mvy074

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