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Possible Role of CYP450 Generated Omega-3/Omega-6 PUFA Metabolites in the Modulation of Blood Pressure and Vascular Function in Obese Children

Obesity is often accompanied by metabolic and haemodynamic disorders such as hypertension, even during childhood. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP450) enzymes to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), vasoactive and natriuretic met...

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Detalles Bibliográficos
Autores principales: Bonafini, Sara, Giontella, Alice, Tagetti, Angela, Marcon, Denise, Montagnana, Martina, Benati, Marco, Gaudino, Rossella, Cavarzere, Paolo, Karber, Mirjam, Rothe, Michael, Minuz, Pietro, Antoniazzi, Franco, Maffeis, Claudio, Schunck, Wolf Hagen, Fava, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267577/
https://www.ncbi.nlm.nih.gov/pubmed/30400671
http://dx.doi.org/10.3390/nu10111689