Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma

Glioblastoma, the most frequent and lethal form of glioma, displays chromosome instability and recurrent somatic copy number alterations (SCNA). Chromothripsis and whole genome duplication (WGD) have been recently identified in cancer. In the present study, we analyzed SCNA and determine the ploidy...

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Detalles Bibliográficos
Autores principales: Boisselier, Blandine, Dugay, Frédéric, Belaud-Rotureau, Marc-Antoine, Coutolleau, Anne, Garcion, Emmanuel, Menei, Philippe, Guardiola, Philippe, Rousseau, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267593/
https://www.ncbi.nlm.nih.gov/pubmed/30542515
http://dx.doi.org/10.18632/oncotarget.26330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267593/
https://www.ncbi.nlm.nih.gov/pubmed/30542515
http://dx.doi.org/10.18632/oncotarget.26330

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