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Whole genome duplication is an early event leading to aneuploidy in IDH-wild type glioblastoma
Glioblastoma, the most frequent and lethal form of glioma, displays chromosome instability and recurrent somatic copy number alterations (SCNA). Chromothripsis and whole genome duplication (WGD) have been recently identified in cancer. In the present study, we analyzed SCNA and determine the ploidy...
Autores principales: | Boisselier, Blandine, Dugay, Frédéric, Belaud-Rotureau, Marc-Antoine, Coutolleau, Anne, Garcion, Emmanuel, Menei, Philippe, Guardiola, Philippe, Rousseau, Audrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267593/ https://www.ncbi.nlm.nih.gov/pubmed/30542515 http://dx.doi.org/10.18632/oncotarget.26330 |
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