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NY-ESO-1 antigen expression and immune response are associated with poor prognosis in MAGE-A4-vaccinated patients with esophageal or head/neck squamous cell carcinoma

MAGE-A4 antigen is a cancer-testis antigen that is frequently expressed in tumor tissues. Cholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical outcomes of patients who received a CHP-MAGE-A4 vaccine. Twenty-...

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Detalles Bibliográficos
Autores principales: Ueda, Shugo, Miyahara, Yoshihiro, Nagata, Yasuhiro, Sato, Eiichi, Shiraishi, Taizo, Harada, Naozumi, Ikeda, Hiroaki, Shiku, Hiroshi, Kageyama, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267599/
https://www.ncbi.nlm.nih.gov/pubmed/30542513
http://dx.doi.org/10.18632/oncotarget.26323