Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Roots of Saussurea lappa C.B.Clarke

Activity-guided fractionation of a MeOH extract of the roots of Saussurea lappa C.B.Clarke (Compositae), using an in vitro protein tyrosine phosphatase 1B (PTP1B) inhibition assay, led to the isolation of four active constituents: betulinic acid (1), betulinic acid methyl ester (2), mokko lactone (3...

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Detalles Bibliográficos
Autores principales: Choi, Ji Young, Na, MinKyun, Hyun Hwang, In, Ho Lee, Seung, Young Bae, Eun, Yeon Kim, Bo, Seog Ahn, Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267619/
https://www.ncbi.nlm.nih.gov/pubmed/19136914
http://dx.doi.org/10.3390/molecules14010266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267619/
https://www.ncbi.nlm.nih.gov/pubmed/19136914
http://dx.doi.org/10.3390/molecules14010266

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