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Autophagy modulation: a prudent approach in cancer treatment?

Autophagy is a tightly controlled process comprising lysosomal degradation and recycling of cellular proteins and organelles. In cancer, its paradoxical dual role of cytoprotection and cytotoxicity is context-dependent and controversial. Autophagy primarily acts as a mechanism of tumour suppression,...

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Detalles Bibliográficos
Autores principales: Bishop, Eleanor, Bradshaw, Tracey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267659/
https://www.ncbi.nlm.nih.gov/pubmed/30182146
http://dx.doi.org/10.1007/s00280-018-3669-6