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Autophagy modulation: a prudent approach in cancer treatment?
Autophagy is a tightly controlled process comprising lysosomal degradation and recycling of cellular proteins and organelles. In cancer, its paradoxical dual role of cytoprotection and cytotoxicity is context-dependent and controversial. Autophagy primarily acts as a mechanism of tumour suppression,...
Autores principales: | Bishop, Eleanor, Bradshaw, Tracey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267659/ https://www.ncbi.nlm.nih.gov/pubmed/30182146 http://dx.doi.org/10.1007/s00280-018-3669-6 |
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