Schisandrin B elicits the Keap1-Nrf2 defense system via carbene reactive metabolite which is less harmful to mice liver

BACKGROUND: Schisandrin B (Sch B) a main active component of Schisandra chinensis, has been shown to act as a liver protectant via activation of the Nrf2 pathway. Nevertheless, it remains unclear whether its reactive metabolite is responsible for Nrf2 activation; also, the effects of its reactive me...

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Detalles Bibliográficos
Autores principales: Feng, Shan, Qiu, Bingxun, Zou, Li, Liu, Ke, Xu, Xiaoyu, Zhu, Huifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267698/
https://www.ncbi.nlm.nih.gov/pubmed/30568426
http://dx.doi.org/10.2147/DDDT.S176561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267698/
https://www.ncbi.nlm.nih.gov/pubmed/30568426
http://dx.doi.org/10.2147/DDDT.S176561

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