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Identification of mTOR inhibitor-resistant genes in cutaneous squamous cell carcinoma

PURPOSE: The PI3K/AKT/mTOR pathway is frequently activated in various squamous cell carcinomas (SCCs). Although mTOR inhibitors are suggested as effective treatments in immunosuppressed patients with metastatic SCC, they are still not proven to be favorable in treating skin SCC patients not undergoi...

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Detalles Bibliográficos
Autores principales: Yu, Seong-Lan, Lee, Dong Chul, Baek, Seung Woo, Cho, Do Yeun, Choi, Jong Gwon, Kang, JaeKu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267733/
https://www.ncbi.nlm.nih.gov/pubmed/30568499
http://dx.doi.org/10.2147/CMAR.S174966