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Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma

INTRODUCTION: Human malignant melanoma (MM) is a highly malignant tumor of cutaneous melanocytes with a fast progression. We investigated the cellular effects of pyrroline-5- carboxylate reductase 1 (PYCR1) in the MM cell lines, A375 and M14. METHODS: Cell Counting Kit-8 assay, transwell assay, and...

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Detalles Bibliográficos
Autores principales: Ye, Yingyi, Wu, Yingying, Wang, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267761/
https://www.ncbi.nlm.nih.gov/pubmed/30568501
http://dx.doi.org/10.2147/CMAR.S166711