Cargando…

Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma

INTRODUCTION: Human malignant melanoma (MM) is a highly malignant tumor of cutaneous melanocytes with a fast progression. We investigated the cellular effects of pyrroline-5- carboxylate reductase 1 (PYCR1) in the MM cell lines, A375 and M14. METHODS: Cell Counting Kit-8 assay, transwell assay, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Yingyi, Wu, Yingying, Wang, Jinyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267761/ https://www.ncbi.nlm.nih.gov/pubmed/30568501 http://dx.doi.org/10.2147/CMAR.S166711

Ejemplares similares

Pyrroline-5-carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non-small cell lung cancer
por: Cai, Feng, et al.
Publicado: (2018)

Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells
por: Zhang, Junli, et al.
Publicado: (2022)

Functional properties and structural characterization of rice δ(1)-pyrroline-5-carboxylate reductase
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Evolution of plant δ(1)-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway
por: Yin, Feng, et al.
Publicado: (2021)

Functional Characterization of Four Putative δ(1)-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis
por: Forlani, Giuseppe, et al.
Publicado: (2017)

Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities
por: Lebreton, Sandrine, et al.
Publicado: (2020)

LINC00511 aggravates the malignancy of lung adenocarcinoma through sponging microRNA miR‐4739 to regulate pyrroline‐5‐carboxylate reductase 1 expression
por: Ye, Lu, et al.
Publicado: (2022)

Functional Impact of a Cancer-Related Variant in Human Δ(1)-Pyrroline-5-Carboxylate Reductase 1
por: Daudu, Oseeyi I., et al.
Publicado: (2023)

Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress
por: Cui, Bai, et al.
Publicado: (2023)

MicroRNA hsa-miR-150-5p inhibits nasopharyngeal carcinogenesis by suppressing PYCR1 (pyrroline-5-carboxylate reductase 1)
por: Li, Zhiqun, et al.
Publicado: (2021)

The structure of Medicago truncatula δ(1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants
por: Ruszkowski, Milosz, et al.
Publicado: (2015)

Preparation of Phosphonic Acid Analogues of Proline and Proline Analogues and Their Biological Evaluation as δ(1)-Pyrroline-5-carboxylate Reductase Inhibitors
por: Qian, Renzhe, et al.
Publicado: (2018)

Pyrroline-5-carboxylate reductase 1 (PYCR1) upregulation contributes to gastric cancer progression and indicates poor survival outcome
por: Xiao, Shiyu, et al.
Publicado: (2020)

Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis
por: Oudaert, Inge, et al.
Publicado: (2022)

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-like/Wnt/β-Catenin Signaling
por: Lama Tamang, Raju, et al.
Publicado: (2023)

Pyrroline-5-Carboxylate Reductase 1 Directs the Cartilage Protective and Regenerative Potential of Murphy Roths Large Mouse Mesenchymal Stem Cells
por: Tejedor, Gautier, et al.
Publicado: (2021)

Δ(1)-Pyrroline-5-Carboxylate/Glutamate Biogenesis Is Required for Fungal Virulence and Sporulation
por: Yao, Ziting, et al.
Publicado: (2013)

Role of proline and pyrroline-5-carboxylate metabolism in plant defense against invading pathogens
por: Qamar, Aarzoo, et al.
Publicado: (2015)

Enzymology and Regulation of δ(1)-Pyrroline-5-Carboxylate Synthetase 2 From Rice
por: Sabbioni, Giuseppe, et al.
Publicado: (2021)

Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II
por: Merx, Jona, et al.
Publicado: (2022)

1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis
por: Yan, Yutao, et al.
Publicado: (2018)

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling
por: Kumar, Santosh, et al.
Publicado: (2023)

Celastrol Combats Methicillin‐Resistant Staphylococcus aureus by Targeting Δ(1)‐Pyrroline‐5‐Carboxylate Dehydrogenase
por: Yuan, Zhongwei, et al.
Publicado: (2023)

MicroRNA-362-5p promotes the proliferation and inhibits apoptosis of trophoblast cells via targeting glutathione-disulfide reductase
por: Zhang, Cuihua, et al.
Publicado: (2021)

Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria
por: Watanabe, Seiya, et al.
Publicado: (2014)

Metal-mediated synthesis of pyrrolines
por: Medran, Noelia S., et al.
Publicado: (2019)

The p75(NTR) and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway
por: Zhong, Maojiao, et al.
Publicado: (2020)

The Δ1-pyrroline-5-carboxylate synthetase family performs diverse physiological functions in stress responses in pear (Pyrus betulifolia)
por: Ma, Changqing, et al.
Publicado: (2022)

Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway
por: Zhang, Qianqian, et al.
Publicado: (2019)

Syntheses and Study of a Pyrroline Nitroxide Condensed Phospholene Oxide and a Pyrroline Nitroxide Attached Diphenylphosphine
por: Isbera, Mostafa, et al.
Publicado: (2021)

Biphenyl-4,4′-diyl bis(2,2,5,5-tetramethyl-1-oxyl-3-pyrroline-3-carboxylate)
por: Margraf, Dominik, et al.
Publicado: (2009)

UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway
por: Ye, Yingyi, et al.
Publicado: (2019)

Fibronectin 1 promotes melanoma proliferation and metastasis by inhibiting apoptosis and regulating EMT
por: Li, Bifei, et al.
Publicado: (2019)

Structural Studies of Yeast Δ(1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State
por: Pemberton, Travis A., et al.
Publicado: (2014)

Functional characterization and expression analysis of rice δ(1)-pyrroline-5-carboxylate dehydrogenase provide new insight into the regulation of proline and arginine catabolism
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Ornithine cyclodeaminase/μ-crystallin homolog from the hyperthermophilic archaeon Thermococcus litoralis functions as a novel Δ(1)-pyrroline-2-carboxylate reductase involved in putative trans-3-hydroxy-l-proline metabolism
por: Watanabe, Seiya, et al.
Publicado: (2014)

Trametes versicolor carboxylate reductase uncovered
por: Winkler, Margit, et al.
Publicado: (2016)

On the chemistry of 1-pyrroline in solution and in the gas phase
por: Zhang, Xiaoping, et al.
Publicado: (2017)

Syntheses and Reactions of Pyrroline, Piperidine Nitroxide Phosphonates
por: Isbera, Mostafa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ua1du7i04eat84g52scm00elv9