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IL-17A contributes to perioperative neurocognitive disorders through blood-brain barrier disruption in aged mice
BACKGROUND: Perioperative neurocognitive disorders (PND) occur frequently after surgery, especially in aged patients. Surgery-induced neuroinflammation and blood-brain barrier (BBB) dysfunction play a crucial role in the pathogenesis of PND. Interleukin-17A (IL-17A) increases after surgical stress a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267879/ https://www.ncbi.nlm.nih.gov/pubmed/30501622 http://dx.doi.org/10.1186/s12974-018-1374-3 |