Enhanced sensitivity to cholera toxin in female ADP-ribosylarginine hydrolase (ARH1)-deficient mice

Cholera toxin, an 84-kDa multimeric protein and a major virulence factor of Vibrio cholerae, uses the ADP-ribosyltransferase activity of its A subunit to intoxicate host cells. ADP-ribosylation is a posttranslational modification of proteins, in which the ADP-ribose moiety of NAD(+) is transferred t...

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Detalles Bibliográficos
Autores principales: Watanabe, Kizuku, Kato, Jiro, Zhu, Jianfeng, Oda, Hirotake, Ishiwata-Endo, Hiroko, Moss, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267974/
https://www.ncbi.nlm.nih.gov/pubmed/30500844
http://dx.doi.org/10.1371/journal.pone.0207693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267974/
https://www.ncbi.nlm.nih.gov/pubmed/30500844
http://dx.doi.org/10.1371/journal.pone.0207693

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