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Towards a molecular basis of ubiquitin signaling: A dual-scale simulation study of ubiquitin dimers
Covalent modification of proteins by ubiquitin or ubiquitin chains is one of the most prevalent post-translational modifications in eukaryotes. Different types of ubiquitin chains are assumed to selectively signal respectively modified proteins for different fates. In support of this hypothesis, str...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268000/ https://www.ncbi.nlm.nih.gov/pubmed/30444864 http://dx.doi.org/10.1371/journal.pcbi.1006589 |