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Towards a molecular basis of ubiquitin signaling: A dual-scale simulation study of ubiquitin dimers

Covalent modification of proteins by ubiquitin or ubiquitin chains is one of the most prevalent post-translational modifications in eukaryotes. Different types of ubiquitin chains are assumed to selectively signal respectively modified proteins for different fates. In support of this hypothesis, str...

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Detalles Bibliográficos
Autores principales: Berg, Andrej, Kukharenko, Oleksandra, Scheffner, Martin, Peter, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268000/
https://www.ncbi.nlm.nih.gov/pubmed/30444864
http://dx.doi.org/10.1371/journal.pcbi.1006589