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Acetylcholinesterase-Inhibiting Activity of Salicylanilide N-Alkylcarbamates and Their Molecular Docking

A series of twenty-five novel salicylanilide N-alkylcarbamates were investigated as potential acetylcholinesterase inhibitors. The compounds were tested for their ability to inhibit acetylcholinesterase (AChE) from electric eel (Electrophorus electricus L.). Experimental lipophilicity was determined...

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Detalles Bibliográficos
Autores principales: Imramovsky, Ales, Stepankova, Sarka, Vanco, Jan, Pauk, Karel, Monreal-Ferriz, Juana, Vinsova, Jarmila, Jampilek, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268027/
https://www.ncbi.nlm.nih.gov/pubmed/22922284
http://dx.doi.org/10.3390/molecules170910142