New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate

A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)(3), in order to generate a carbon-carbon bond between a terminal alkene and malonate. Derivatives 1–8 were obtained in moderate to good yields under mild conditions. This key st...

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Detalles Bibliográficos
Autores principales: Bouhlel, Ahlem, Curti, Christophe, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268072/
https://www.ncbi.nlm.nih.gov/pubmed/22491680
http://dx.doi.org/10.3390/molecules17044313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268072/
https://www.ncbi.nlm.nih.gov/pubmed/22491680
http://dx.doi.org/10.3390/molecules17044313

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