A New Method for Production of Chiral 2-Aryl-2-fluoropropanoic Acids Using an Effective Kinetic Resolution of Racemic 2-Aryl-2-fluoropropanoic Acids

We report a new method for the preparation of chiral 2-aryl-2-fluoropropanoic acids, including 2-fluoroibuprofen, a fluorinated analogue of non-steroidal anti-inflammatory drugs (NSAIDs), by the kinetic resolution of racemic 2-aryl-2-fluoropropanoic acids using enantioselective esterification. By ap...

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Detalles Bibliográficos
Autores principales: Tengeiji, Atsushi, Shiina, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268090/
https://www.ncbi.nlm.nih.gov/pubmed/22699569
http://dx.doi.org/10.3390/molecules17067356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268090/
https://www.ncbi.nlm.nih.gov/pubmed/22699569
http://dx.doi.org/10.3390/molecules17067356

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