Total Synthesis and Antidepressant Activities of Laetispicine and Its Derivatives

The first total synthesis of laetispicine (1a), an amide alkaloid isolated from the stems of Piper laetispicum C.DC (Piperaceae), and the synthesis of some of its derivatives were described. Based on the evaluation of antidepressant activities in the forced swimming test, compounds 1h and 1i were id...

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Detalles Bibliográficos
Autores principales: Yao, Shuyi, Xie, Hui, Zhang, Li, Meng, Tao, Zhang, Yongliang, Wang, Xin, Chen, Lin, Pan, Shengli, Shen, Jingkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268093/
https://www.ncbi.nlm.nih.gov/pubmed/22306832
http://dx.doi.org/10.3390/molecules17021425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268093/
https://www.ncbi.nlm.nih.gov/pubmed/22306832
http://dx.doi.org/10.3390/molecules17021425

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