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Synthesis and 5α-Reductase Inhibitory Activity of C(21) Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
The synthesis and evaluation of 5α-reductase inhibitory activity of some 4-azasteroid-20-ones and 20-oximes and 3β-hydroxy-, 3β-acetoxy-, or epoxy-substituted C(21) steroidal 20-ones and 20-oximes having double bonds in the A and/or B ring are described. Inhibitory activity of synthesized compounds...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268135/ https://www.ncbi.nlm.nih.gov/pubmed/22210173 http://dx.doi.org/10.3390/molecules17010355 |