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Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans

O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting th...

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Detalles Bibliográficos
Autores principales: Hung, Chien-Ya, Tsai, Yu-Cheng, Li, Kuo-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268160/
https://www.ncbi.nlm.nih.gov/pubmed/22960867
http://dx.doi.org/10.3390/molecules170910724
Descripción
Sumario:O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC(50) values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H(2)O(2) scavenging ability, with IC(50) values of 10.5, 23.4, and 13.4 μM, respectively.