Cargando…

Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans

O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting th...

Descripción completa

Detalles Bibliográficos
Autores principales: Hung, Chien-Ya, Tsai, Yu-Cheng, Li, Kuo-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268160/
https://www.ncbi.nlm.nih.gov/pubmed/22960867
http://dx.doi.org/10.3390/molecules170910724
_version_ 1783376225395277824
author Hung, Chien-Ya
Tsai, Yu-Cheng
Li, Kuo-Yu
author_facet Hung, Chien-Ya
Tsai, Yu-Cheng
Li, Kuo-Yu
author_sort Hung, Chien-Ya
collection PubMed
description O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC(50) values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H(2)O(2) scavenging ability, with IC(50) values of 10.5, 23.4, and 13.4 μM, respectively.
format Online
Article
Text
id pubmed-6268160
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62681602018-12-12 Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans Hung, Chien-Ya Tsai, Yu-Cheng Li, Kuo-Yu Molecules Article O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC(50) values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H(2)O(2) scavenging ability, with IC(50) values of 10.5, 23.4, and 13.4 μM, respectively. MDPI 2012-09-07 /pmc/articles/PMC6268160/ /pubmed/22960867 http://dx.doi.org/10.3390/molecules170910724 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hung, Chien-Ya
Tsai, Yu-Cheng
Li, Kuo-Yu
Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title_full Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title_fullStr Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title_full_unstemmed Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title_short Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
title_sort phenolic antioxidants isolated from the flowers of osmanthus fragrans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268160/
https://www.ncbi.nlm.nih.gov/pubmed/22960867
http://dx.doi.org/10.3390/molecules170910724
work_keys_str_mv AT hungchienya phenolicantioxidantsisolatedfromtheflowersofosmanthusfragrans
AT tsaiyucheng phenolicantioxidantsisolatedfromtheflowersofosmanthusfragrans
AT likuoyu phenolicantioxidantsisolatedfromtheflowersofosmanthusfragrans