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Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans
O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268160/ https://www.ncbi.nlm.nih.gov/pubmed/22960867 http://dx.doi.org/10.3390/molecules170910724 |
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author | Hung, Chien-Ya Tsai, Yu-Cheng Li, Kuo-Yu |
author_facet | Hung, Chien-Ya Tsai, Yu-Cheng Li, Kuo-Yu |
author_sort | Hung, Chien-Ya |
collection | PubMed |
description | O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC(50) values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H(2)O(2) scavenging ability, with IC(50) values of 10.5, 23.4, and 13.4 μM, respectively. |
format | Online Article Text |
id | pubmed-6268160 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62681602018-12-12 Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans Hung, Chien-Ya Tsai, Yu-Cheng Li, Kuo-Yu Molecules Article O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl(3) sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC(50) values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H(2)O(2) scavenging ability, with IC(50) values of 10.5, 23.4, and 13.4 μM, respectively. MDPI 2012-09-07 /pmc/articles/PMC6268160/ /pubmed/22960867 http://dx.doi.org/10.3390/molecules170910724 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Hung, Chien-Ya Tsai, Yu-Cheng Li, Kuo-Yu Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title | Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title_full | Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title_fullStr | Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title_full_unstemmed | Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title_short | Phenolic Antioxidants Isolated from the Flowers of Osmanthus fragrans |
title_sort | phenolic antioxidants isolated from the flowers of osmanthus fragrans |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268160/ https://www.ncbi.nlm.nih.gov/pubmed/22960867 http://dx.doi.org/10.3390/molecules170910724 |
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