Condensation Reactions of 3-Oxo-2-arylhydrazonopropanals with Active Methylene Reagents: Formation of 2-Hydroxy- and 2-Amino-6-substituted-5-arylazonicotinates and Pyrido[3,2-c]cinnolines via 6π-Electrocyclization Reactions

3-Oxo-3-phenyl-2-(p-tolylhydrazono)propanal (1a) undergoes condensation with ethyl cyanoacetate in acetic acid in the presence of ammonium acetate to yield either 2-hydroxy-6-phenyl-5-p-tolylazonicotinic acid ethyl ester (6a) or 2-amino-6-phenyl-5-p-tolyl-azonicotinic acid ethyl ester (8), depending...

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Detalles Bibliográficos
Autores principales: Al-Mousawi, Saleh M., El-Apasery, Morsy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268191/
https://www.ncbi.nlm.nih.gov/pubmed/22728352
http://dx.doi.org/10.3390/molecules17066547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268191/
https://www.ncbi.nlm.nih.gov/pubmed/22728352
http://dx.doi.org/10.3390/molecules17066547

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