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Synthesis of Amino Core Compounds of Galactosyl Phytosyl Ceramide Analogs for Developing iNKT-Cell Inducers

1-Aminophytosphingosine and 6-aminogalactosyl phytosphingosine were prepared in 61% and 40% yield libraries with 44 carboxylic acids showed that a 4-butylbenzoic acid-derived product exe, respectively. Glycosylation using benzoyl-protected lipid resulted in better α-selectivity for ceramide analogs,...

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Detalles Bibliográficos
Autores principales: Huang, Yin-Cheng, Chiang, Li-Wu, Chang, Kai-Shiang, Su, Wen-Chin, Lin, Yi-Hsian, Jeng, Kee-Ching, Lin, Kun-I, Liao, Kuo-Yen, Huang, Ho-Lein, Yu, Chung-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268237/
https://www.ncbi.nlm.nih.gov/pubmed/22410417
http://dx.doi.org/10.3390/molecules17033058