FG020326 Sensitized Multidrug Resistant Cancer Cells to Docetaxel-Mediated Apoptosis via Enhancement of Caspases Activation

Apoptotic resistance is the main obstacle for treating cancer patients with chemotherapeutic drugs. Multidrug resistance (MDR) is often characterized by the expression of P-glycoprotein (P-gp), a 170-KD ATP-dependent drug efflux protein. Functional P-gp can confer resistance to activate caspase-8 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiu-Wen, Wang, Xiao-Kun, Zhang, Xu, Liang, Yong-Ju, Shi, Zhi, Chen, Li-Ming, Fu, Li-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268253/
https://www.ncbi.nlm.nih.gov/pubmed/22572929
http://dx.doi.org/10.3390/molecules17055442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268253/
https://www.ncbi.nlm.nih.gov/pubmed/22572929
http://dx.doi.org/10.3390/molecules17055442

Ejemplares similares