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FG020326 Sensitized Multidrug Resistant Cancer Cells to Docetaxel-Mediated Apoptosis via Enhancement of Caspases Activation

Apoptotic resistance is the main obstacle for treating cancer patients with chemotherapeutic drugs. Multidrug resistance (MDR) is often characterized by the expression of P-glycoprotein (P-gp), a 170-KD ATP-dependent drug efflux protein. Functional P-gp can confer resistance to activate caspase-8 an...

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Detalles Bibliográficos
Autores principales:	Wang, Xiu-Wen, Wang, Xiao-Kun, Zhang, Xu, Liang, Yong-Ju, Shi, Zhi, Chen, Li-Ming, Fu, Li-Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268253/ https://www.ncbi.nlm.nih.gov/pubmed/22572929 http://dx.doi.org/10.3390/molecules17055442

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