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Synthesis of New Indole Derivatives Structurally Related to Donepezil and Their Biological Evaluation as Acetylcholinesterase Inhibitors

New series of indole derivatives analogous to donepezil, a well known anti-Alzheimer and acetylcholinesterase inhibitor drug, was synthesized. A full chemical characterization of the new compounds is provided. Biological evaluation of the new compounds as acetylcholinesterase inhibitors was performe...

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Detalles Bibliográficos
Autores principales: Ismail, Mohamed M., Kamel, Mona M., Mohamed, Lamia W., Faggal, Samar I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268345/
https://www.ncbi.nlm.nih.gov/pubmed/22534665
http://dx.doi.org/10.3390/molecules17054811