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Synthesis and Biological Evaluation of New Ligustrazine Derivatives as Anti-Tumor Agents

To discover new anti-cancer agents with multi-effect and low toxicity, a series of ligustrazine derivatives were synthesized using several effective anti-tumor ingredients of Shiquandabu Wan as starting materials. Our idea was enlightened by the “combination principle” in drug discovery. The ligustr...

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Detalles Bibliográficos
Autores principales: Wang, Penglong, She, Gaimei, Yang, Yanan, Li, Qiang, Zhang, Honggui, Liu, Jie, Cao, Yinqiu, Xu, Xin, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268357/
https://www.ncbi.nlm.nih.gov/pubmed/22547319
http://dx.doi.org/10.3390/molecules17054972