Identification of Fungicidal 2,6-Disubstituted Quinolines with Activity against Candida Biofilms

We have identified two subseries of 2,6-disubstituted quinolines, consisting of 6-amide and 6-urea derivatives, which are characterized by fungicidal activity against Candida albicans with minimal fungicidal concentration (MFC) values < 15 µM. The 6-amide derivatives displayed the highest fungici...

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Detalles Bibliográficos
Autores principales: Delattin, Nicolas, Bardiot, Dorothée, Marchand, Arnaud, Chaltin, Patrick, De Brucker, Katrijn, Cammue, Bruno P. A., Thevissen, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268363/
https://www.ncbi.nlm.nih.gov/pubmed/23079495
http://dx.doi.org/10.3390/molecules171012243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268363/
https://www.ncbi.nlm.nih.gov/pubmed/23079495
http://dx.doi.org/10.3390/molecules171012243

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