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Parallel Synthesis of 2-Substituted 6-(5-Oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides

A library of 24 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides 10{1,2; 1–12} was prepared by a parallel solution-phase approach. The synthesis comprises a five-step transformation of itaconic acid (11) into 1-methyl and 1-phenyl substituted 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-c...

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Detalles Bibliográficos
Autores principales: Črček, Bojana, Baškovč, Jernej, Grošelj, Uroš, Kočar, Drago, Dahmann, Georg, Stanovnik, Branko, Svete, Jurij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268364/
https://www.ncbi.nlm.nih.gov/pubmed/22569416
http://dx.doi.org/10.3390/molecules17055363