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Antifungal Activity of Homoaconitate and Homoisocitrate Analogs

Thirteen structural analogs of two initial intermediates of the l-α-aminoadipate pathway of l-lysine biosynthesis in fungi have been designed and synthesized, including fluoro- and epoxy-derivatives of homoaconitate and homoisocitrate. Some of the obtained compounds exhibited at milimolar range mode...

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Detalles Bibliográficos
Autores principales: Milewska, Maria J., Prokop, Marta, Gabriel, Iwona, Wojciechowski, Marek, Milewski, Sławomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268379/
https://www.ncbi.nlm.nih.gov/pubmed/23187286
http://dx.doi.org/10.3390/molecules171214022