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Hydrogel of Ketoconazole and PAMAM Dendrimers: Formulation and Antifungal Activity

Ketoconazole (KET), an imidazole derivative with well-known antifungal properties, is lipophilic and practically insoluble in water, therefore its clinical use has some practical disadvantages. The aim of the present study was to investigate the influence of PAMAM-NH(2) and PAMAM-OH dendrimers gener...

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Detalles Bibliográficos
Autores principales: Winnicka, Katarzyna, Wroblewska, Magdalena, Wieczorek, Piotr, Sacha, Pawel Tomasz, Tryniszewska, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268403/
https://www.ncbi.nlm.nih.gov/pubmed/22513487
http://dx.doi.org/10.3390/molecules17044612