Cargando…

Synthesis of New 1,3,4-Thiadiazole and 1,2,3,4-Oxathiadiazole Derivatives from Carbohydrate Precursors and Study of Their Effect on Tyrosinase Enzyme

5-(1,2,3,4-Tetrahydroxybutyl)-2-methylfuran-3-carbohydrazide (2) was condensed with a variety of ketones to afford carbohydrazide derivatives 3–6. Acetylation of 3–5 afforded the acetyl derivatives 7–9, while periodate oxidation of 3–6 afforded the formyl derivatives 10–13. Acid catalyzed condensati...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Sadek, Mohamed M., Hassan, Seham Y., Abdelwahab, Huda E., Yacout, Galila A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268412/
https://www.ncbi.nlm.nih.gov/pubmed/22785266
http://dx.doi.org/10.3390/molecules17078378