c-IAP1 Binds and Processes PCSK9 Protein: Linking the c-IAP1 in a TNF-α Pathway to PCSK9-Mediated LDLR Degradation Pathway

Recent genetic studies have shown that PCSK9, one of the key genes in cholesterol metabolism, plays a critical role by controlling the level of low-density lipoprotein receptor. However, how PCSK9 mediates LDLR degradation is still unknown. By combining a shotgun proteomic method and differential an...

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Detalles Bibliográficos
Autores principales: Xu, Weiming, Liu, Lizhi, Hornby, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268524/
https://www.ncbi.nlm.nih.gov/pubmed/23085658
http://dx.doi.org/10.3390/molecules171012086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268524/
https://www.ncbi.nlm.nih.gov/pubmed/23085658
http://dx.doi.org/10.3390/molecules171012086

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