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Synthesis, Characterization and Cytotoxicity of New Rotundic Acid Derivatives

Rotundic acid (RA, 1), a natural compound, exhibits potent tumor cell growth inhibiting properties. To date there are no reports on derivatives of RA. Furthermore, the 28-COOH position of RA might make it unstable and induced serious gastrointestinal side effects when it was applied in vivo. Therefo...

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Detalles Bibliográficos
Autores principales: He, Yu-Fang, Nan, Min-Lun, Sun, Jia-Ming, Meng, Zhao-Jie, Yue, Fa-Gui, Zhao, Quan-Cheng, Yang, Xiao-Hong, Wang,  Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268532/
https://www.ncbi.nlm.nih.gov/pubmed/22293846
http://dx.doi.org/10.3390/molecules17021278