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Preparation of Novel meta- and para-Substituted N-Benzyl Protected Quinuclidine Esters and Their Resolution with Butyrylcholinesterase

Since the optically active quinuclidin-3-ol is an important intermediate in the preparation of physiologically or pharmacologically active compounds, a new biocatalytic method for the production of chiral quinuclidin-3-ols was examined. Butyrylcholinesterase (BChE; EC 3.1.1.8) was chosen as a biocat...

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Detalles Bibliográficos
Autores principales: Primožič, Ines, Bolant, Marijana, Ramić, Alma, Tomić, Srđanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268536/
https://www.ncbi.nlm.nih.gov/pubmed/22249408
http://dx.doi.org/10.3390/molecules17010786