A PAMPA Assay as Fast Predictive Model of Passive Human Skin Permeability of New Synthesized Corticosteroid C-21 Esters

The permeation properties of twenty newly synthesized α-alkoxyalkanoyl and α-aryloxyalkanoyl C-21 esters of standard corticosteroids: Fluocinolone acetonide, dexamethasone, triamcinolone acetonide and hydrocortisone were established using a PAMPA assay (70% silicone oil and 30% isopropyl myristate)....

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Detalles Bibliográficos
Autores principales: Markovic, Bojan D., Vladimirov, Sote M., Cudina, Olivera A., Odovic, Jadranka V., Karljikovic-Rajic, Katarina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268546/
https://www.ncbi.nlm.nih.gov/pubmed/22222907
http://dx.doi.org/10.3390/molecules17010480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268546/
https://www.ncbi.nlm.nih.gov/pubmed/22222907
http://dx.doi.org/10.3390/molecules17010480

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