Synthesis and Bioactivity of Pyrazole Acyl Thiourea Derivatives

Sixteen novel pyrazole acyl thiourea derivatives 6 were synthesized from monomethylhydrazine (phenylhydrazine) and ethyl acetoacetate. The key 5-chloro-3-methyl-1-substituted-1H-pyrazole-4-carbonyl chloride intermediates 4 were first generated in four steps through cyclization, formylation, oxidatio...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Shi, Qing, Chen, Zhuo, He, Ming, Jin, Linhong, Hu, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268560/
https://www.ncbi.nlm.nih.gov/pubmed/22555301
http://dx.doi.org/10.3390/molecules17055139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268560/
https://www.ncbi.nlm.nih.gov/pubmed/22555301
http://dx.doi.org/10.3390/molecules17055139

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