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Regiocontrolled Microwave Assisted Bifunctionalization of 7,8-Dihalogenated Imidazo[1,2-a]pyridines: A One Pot Double-Coupling Approach

The reactivity of the 7-chloro-8-iodo- and 8-chloro-7-iodoimidazo[1,2-a]pyridines 1a–e diversely substituted on the 2 position, towards Suzuki-Miyaura, Sonogashira, and Buchwald-Hartwig cross-coupling reactions as well as cyanation was evaluated. Various methodologies are proposed to introduce aryl,...

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Detalles Bibliográficos
Autores principales: Marie, Emilie, Bouclé, Sébastien, Enguehard-Gueiffier, Cécile, Gueiffier, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268566/
https://www.ncbi.nlm.nih.gov/pubmed/22955457
http://dx.doi.org/10.3390/molecules170910683