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Synthesis, Molecular Properties Prediction, and Anti-staphylococcal Activity of N-Acylhydrazones and New 1,3,4-Oxadiazole Derivatives

Five new 1-(2-(5-nitrofuran-2-yl)-5-(aryl)-1,3,4-oxadiazol-3-(2H)-yl) ethanone compounds 5a–e were synthesized by cyclization of N-acylhydrazones 4a–e with acetic anhydride under reflux conditions. Their structures were fully characterized by IR, (1)H-NMR, and (13)C-NMR. Furthermore, evaluations of...

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Detalles Bibliográficos
Autores principales: de Oliveira, Cledualdo Soares, Lira, Bruno Freitas, dos Santos Falcão-Silva, Vivyanne, Siqueira-Junior, Jose Pinto, Barbosa-Filho, Jose Maria, de Athayde-Filho, Petronio Filgueiras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268585/
https://www.ncbi.nlm.nih.gov/pubmed/22555298
http://dx.doi.org/10.3390/molecules17055095