Asymmetric Construction of All-Carbon Quaternary Stereocenters by Chiral-Auxiliary-Mediated Claisen Rearrangement and Total Synthesis of (+)-Bakuchiol

An asymmetric Claisen rearrangement using Oppolzer’s camphorsultam was developed. Under thermal conditions, a geraniol-derived substrate underwent the rearrangement with good stereoselectivity. The absolute configuration of the newly formed all-carbon quaternary stereocenter was confirmed by the tot...

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Detalles Bibliográficos
Autores principales: Takao, Ken-ichi, Sakamoto, Shu, Touati, Marianne Ayaka, Kusakawa, Yusuke, Tadano, Kin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268616/
https://www.ncbi.nlm.nih.gov/pubmed/23138536
http://dx.doi.org/10.3390/molecules171113330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268616/
https://www.ncbi.nlm.nih.gov/pubmed/23138536
http://dx.doi.org/10.3390/molecules171113330

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