Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response

In this paper we report the design, synthesis and pharmacological evaluation of a new series of phenyl sulfonamide derivatives 2a–h and 3–8 planned by structural modification on the anti-inflammatory prototype LASSBio-468 (1). Among the synthesized analogues, the tetrafluorophthalimide LASSBio-1439...

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Detalles Bibliográficos
Autores principales: de Castro Barbosa, Maria Letícia, Ramos, Thiago José Figueira, de Arantes, Ana Carolina Santos, Martins, Marco Aurélio, Silva, Patrícia Machado Rodrigues e, Barreiro, Eliezer J., Lima, Lídia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268662/
https://www.ncbi.nlm.nih.gov/pubmed/23222927
http://dx.doi.org/10.3390/molecules171214651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268662/
https://www.ncbi.nlm.nih.gov/pubmed/23222927
http://dx.doi.org/10.3390/molecules171214651

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