Synthesis and Antibacterial Activities of Amphiphilic Neomycin B-based Bilipid Conjugates and Fluorinated Neomycin B-based Lipids

Investigating the effect of lipid hydrophobicity on the activity of amphiphilic neomycin B conjugates, six polycationic amphiphiles (PAs) were created. Four of the new compounds incorporated either palmitic or arachidic di-lipid lysine tails, while two had single fluorinated undecanoic acid tails. T...

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Detalles Bibliográficos
Autores principales: Bera, Smritilekha, Dhondikubeer, Ramesh, Findlay, Brandon, Zhanel, George G., Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268716/
https://www.ncbi.nlm.nih.gov/pubmed/22858839
http://dx.doi.org/10.3390/molecules17089129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268716/
https://www.ncbi.nlm.nih.gov/pubmed/22858839
http://dx.doi.org/10.3390/molecules17089129

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