Novel Benzothiazole, Benzimidazole and Benzoxazole Derivatives as Potential Antitumor Agents: Synthesis and Preliminary in Vitro Biological Evaluation

In a previous hit-to-lead research program targeting anticancer agents, two promising lead compounds, 1a and 1b, were found. However, the poor solubility of 1a and 1b made difficult further in vivo studies. To solve this problem, a lead optimization was conducted through introducing N-methyl-piperaz...

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Detalles Bibliográficos
Autores principales: Xiang, Pu, Zhou, Tian, Wang, Liang, Sun, Chang-Yan, Hu, Jing, Zhao, Ying-Lan, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268746/
https://www.ncbi.nlm.nih.gov/pubmed/22252503
http://dx.doi.org/10.3390/molecules17010873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268746/
https://www.ncbi.nlm.nih.gov/pubmed/22252503
http://dx.doi.org/10.3390/molecules17010873

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