Synthesis of a Cholesteryl-HEG Phosphoramidite Derivative and Its Application to Lipid-conjugates of the Anti-HIV (5')TGGGAG(3') Hotoda’s Sequence

A novel phosphoramidite derivative of cholesterol, with an ether-linked hexaethylene glycol (HEG) spacer arm, has been obtained through simple and reproducible solid phase modified oligonucleotide synthesis manipulations. This building block and the known phosphoramidite derivative of 3β-(2-hydroxye...

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Detalles Bibliográficos
Autores principales: Musumeci, Domenica, Montesarchio, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268758/
https://www.ncbi.nlm.nih.gov/pubmed/23090019
http://dx.doi.org/10.3390/molecules171012378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268758/
https://www.ncbi.nlm.nih.gov/pubmed/23090019
http://dx.doi.org/10.3390/molecules171012378

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