Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells

Three aminodi(hetero)arylamines were prepared via a palladium-catalyzed C-N Buchwald-Hartwig coupling of methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate with different bromonitrobenzenes, followed by reduction of the nitro groups of the coupling products to the corresponding amino compounds. The a...

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Detalles Bibliográficos
Autores principales: Calhelha, Ricardo C., Ferreira, Isabel C. F. R., Peixoto, Daniela, Abreu, Rui M. V., Vale-Silva, Luís A., Pinto, Eugénia, Lima, Raquel T., Alvelos, M. Inês, Vasconcelos, M. Helena, Queiroz, Maria-João R. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268773/
https://www.ncbi.nlm.nih.gov/pubmed/22456543
http://dx.doi.org/10.3390/molecules17043834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268773/
https://www.ncbi.nlm.nih.gov/pubmed/22456543
http://dx.doi.org/10.3390/molecules17043834

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